Both players were suspended for last night's win over Juventus and Murphy could replace Dickson Etuhu, who picked up a knock in the Europa League victory.
Andy Johnson and John Pantsil (both knee) are out, David Elm is a doubt with illness while Clint Dempsey is pushing for a starting place after scoring the winner against Juve.
Fulham (from): Schwarzer, Zuberbuhler, Baird, Kelly, Shorey, Stoor, Konchesky, Hangeland, Hughes, Smalling, Gera, Duff, Murphy, Greening, Davies, Etuhu, Riise, Nevland, Elm, Okaka, Zamora, Marsh-Brown