The Cottagers travel to Stoke for the third round of the Carling Cup - the second of three matches in eight days.
Hughes, who was appointed Fulham manager in late July, is ready to select his strongest available line-up once again as he continues to asses the strength of his side.
"I made the point before and after the last round that we are very early in the season and we don't need to make many changes," he said.
"From a new manager's point of view, I want to see the core elements of my team play as much as possible.
"That might be different for other clubs who have managers who know their teams inside out. That is a different situation, but for me it helps seeing them play as many times as I can."