The Fulham defender will likely undergo surgery by the same surgeon who treated David Beckham for his Achilles injury back in March.
Senderos only joined Fulham in June after failing to secure a regular first-team place at Arsenal.
David Beckham is hoping to be fit enough to return to LA Galaxy in September, six months after his surgery. If Senderos is given a similiar prognosis to Beckham, he could be out until January at the earliest.